Can Tottenham take the six pointer?
The ambition for both Liverpool and Tottenham at this stage of the season will be 4th spot and a prestigious place in the Champions League.
A match of this significance could be deemed a six pointer and it is of debate whether this Jekyll and Hyde Spurs side will heap further misery on Rafael Benitez.
Saturday's 1-1 draw with Stoke left Liverpool in seventh place and four points worse off than Tottenham.
Liverpool's superstar core of Steven Gerrard and Fernando Torres will be absent from the team sheet on Wednesday alongside their attacking full back Glen Johnson and Yossi Benayoun.
Liverpool could be lifted though with a full home debut being given to the new Argentinean international midfielder Maxi Rodriguez.
He moved to Liverpool on a free transfer from Atletico Madrid but he is almost the wrong side of thirty and has become injury prone of late.
However, it is unlikely he will last the full ninety minutes with questions being asked of his fitness due to his recent lack of football.
Without the attacking expertise of this quartet, the fringe players will really need to up their game.
Tottenham will be looking to bounce back after their poor no score draw at home to Hull and should be up for their trip North West.
Tottenham will be without Aaron Lennon, Jonathan Woodgate and Ledley King but with more than adequate replacements in the squad they should prove too strong for a Liverpool team that lacks direction without the first team regulars.
On the opening weekend of the season Benoit Assou -Ekotto and Sebastien Bassong scored as Spurs defeated Liverpool 2-1 in North London.
I perceive the value to be Tottenham at even money in the Draw No Bet market.
Although a weakened Liverpool team will walk out that dressing room, Anfield still has an aura and has never been an easy ground to play away from home.
The former Liverpool striker Peter Crouch could come in for the inconsistent Robbie Keane.
Crouch will still be smarting at his treatment from Benitez and 5/4 for him to score at anytime against a vulnerable Liverpool defence and an ageing Carragher could provide value.
For now he is Rafa the Gaffer, but there will be the no consolation for him in what could be Liverpool's defining match of the season and if the Kop go against him it could be adios Anfield!