NFL
NFL Week 17 Predictions: Best Bets This Weekend
It’s the penultimate week of the 2025 NFL regular season and our tipster is here with his best bets for Week 17.
It is do or die time for the teams in contention for the playoffs while the Las Vegas Raiders and New York Giants are going toe-to-toe for the first overall pick in next year’s NFL Draft.
Who will prevail on NFL Sunday this weekend? Only time will tell. Here, I go through my best bets in Week 17 of the NFL ahead of what should be another informative evening of American football as the NFL MVP race, the NFL Draft number one pick and postseason picture becomes a little clearer.
NFL Week 17 Betting Tips:
A big weekend for the NFL teams in playoff contention now. With several postseason berths still up for grabs, victory is essential in the race to reach the playoffs and keep the Super Bowl dream alive. Here, I look through some of the best bets at William Hill for NFL Week 17.
Week 17 NFL Picks Straight Up:
Here are my best NFL picks straight up for Week 17. I believe that these four teams are worth backing on the money line to win and fingers crossed we’ll be celebrating a successful accumulator this weekend:
- Jacksonville Jaguars (at Indianapolis Colts)
- Tampa Bay Buccaneers (at Miami Dolphins)
- Cincinnati Bengals (vs Arizona Cardinals)
- Buffalo Bills (vs Philadelphia Eagles)
At the time of writing, a £10 bet on the four-fold accumulator returns £45.21 – with odds of 3.52/1 on all four teams to win in Week 17.
Who will win the Super Bowl? The postseason picture is taking shape but the fight to win the NFL’s ultimate prize looks wide open and the National Football League playoffs are likely to be competitive as ever.
*Odds subject to change – prices accurate at the time of writing*
