NFL
NFL Week 18 Picks Straight Up, Predictions & Betting Tips
The final gameweek of the 2025/26 National Football League season is here and our tipster is back with his best bets in the NFL on Sunday evening.
It looks like the Las Vegas Raiders, 2-14 heading into the final weekend of the regular season, are likely to secure the first overall pick in the 2026 NFL Draft while the New England Patriots and Denver Broncos are fighting it out for the top seed in the AFC.
We already know the NFC runs through Seattle and that means the Seahawks can rest starters on Sunday evening. That could prove very useful indeed come the business end of the postseason and they are currently favourites at 4/1 to win the Super Bowl.
But let’s not get carried away – the focus remains on the here and now. Who will prevail on NFL Sunday and who will fall short in their pursuit of the playoffs? Only time will tell, so let’s get stuck into it…
NFL Week 18 Betting Tips
A decisive weekend for the NFL teams in playoff contention now. With the postseason picture still murky enough heading into the final weekend of the campaign, victory is essential in the race to reach the playoffs and keep the Super Bowl dream alive. Here, I look through some of the best bets at William Hill for NFL Week 18.
Week 18 NFL Picks Straight Up
Here are my best NFL picks straight up for Week 18. I believe that these four teams are worth backing on the money line to win and fingers crossed we’ll be celebrating a successful accumulator this weekend:
- Houston Texans (vs Indianapolis Colts)
- Chicago Bears (vs Detroit Lions)
- Kansas City Chiefs (at Las Vegas Raiders)
- Philadelphia Eagles (vs Washington Commanders)
At the time of writing, a £10 bet on the four-fold accumulator returns £36.56 – with odds of 2.66/1 on all four teams to win in Week 18.
Who will win the Super Bowl? The postseason picture is taking shape but the fight to win the NFL’s ultimate prize looks wide open and the National Football League playoffs are likely to be competitive as ever.
*Odds subject to change – prices accurate at the time of writing*