The Champions League resumes on Wednesday and we’re in for a treat, with Real Madrid, Manchester City, Lyon and Juventus all in action.

Madrid look Real value

With the Premier League title now out of reach for City, all of their attentions turn to Champions League success – especially with an impending European ban lingering over them. However, the stats suggest the Citizens could be in for a rude awakening when they face the unenviable task of taking on Madrid in the first leg of their last 16 knockout clash. City have never beaten Madrid in competitive action, losing both of their games in Spain while drawing the other two of their four head-to-heads at the Etihad Stadium.

And it doesn’t look any better when you take into consideration Madrid’s fine record in the Champions League, with the Spanish giants prevailing in their last four knockout ties against English sides. That record includes a 5-0 aggregate win against Tottenham, 3-2 defeat of Manchester United, 1-0 victory against Manchester City and 3-1 win against Liverpool in the 2017-18 showpiece final.

When it comes to winning silverware, managers don’t come much more successful than Pep Guardiola and he has had his heart on winning the Champions League with City since arriving. However, in Madrid boss Zinedine Zidane, Guardiola faces a man who has won all 12 Champions League knockout ties he has managed and has won the Champions League three times.

That’s a joint record with Bob Paisley and Carlo Ancelotti, and though Madrid can’t rely on Cristiano Ronaldo anymore, the 2/1 available on the Spanish side winning at the Santiago Bernabeu on Wednesday night is tempting.

Juve got to back Ronaldo and Co

Though a spectacle for the Lyon fans, the thought of welcoming Cristiano Ronaldo and his Juventus team-mates to the Groupama Stadium won’t fill many of them with confidence of reaching the latter stages.

The hosts have reached the knockout stages more times than any other Ligue 1 side, but have tried and failed on four occasions to get the better of Juve, losing both of their home games by a solitary goal. And it doesn’t get any better when you look at historical stats. For example, they haven’t progressed from the last-16 in a decade and have found the net just three times in nine knockout games.

Juventus, meanwhile, have failed to win just one of their last seven Champions League away games in the knockout phase and with Ronaldo at their disposal, a win should be easily achievable. The only surprise is that the Turin side aren’t odds-on, so take advantage of this and back Juventus to win at 21/20 en route to the quarter-finals.

Check out all the latest football betting odds at William Hill